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Objective. To report the prescription of procalcitonin in the diagnosis and monitoring of infectious and inflammatory diseases in Bamako, Mali. Methodology. This was a descriptive prospective study of patients registered between January 1, 2017 and June 30, 2017. We included 253 records of patients in whom Procalcitonin (PCT) was dosed. Results. PCT was prescribed for subjects aged 3 days to 90 years with a mean age of 41.68 ± 22.66 years in men and 40.99 ± 19.14 years in women. The most frequently reported clinical information was renal and infectious tests respectively 33.20% and 23.71%, the least frequent were lung infections and shock. Depending on the degree of severity of the infection in relation to the PCT rate we have: absence of bacterial infection (≤0,25 ng/ml) in 33.99%; localized bacterial infection (0.25 - 0.5 ng/ml) in 5.53%; systemic bacterial infection (0.5 - 2 ng/ml) in 14.23%; severe sepsis (2 - 10 ng/ml) in 18.97%; and septic shock (>10 ng/ml) in 27.27%. Conclusion. PCT was prescribed as part of the renal workup, and in the majority of cases in febrile states. PCT values were predictive of infection. And allows a differential diagnosis between infection and systemic diseases.
Objectif. Présenter les résultats de la prescription du dosage de la procalcitonine dans le diagnostic et le suivi des maladies infectieuses et inflammatoires à Bamako, Mali. Méthodologie. Il s’agit d’une étude transversale descriptive et prospective réalisée entre le 1er janvier et le 30 juin 2017. Nous avons inclus les données de 253 patients chez qui la procalcitonine (PCT) a été dosée dans le sang. Résultats. Le dosage de PCT a été prescrit à des sujets d’âge compris entre 3 jours et 90 ans (moyenne: 41.68 ± 22.66 ans chez les hommes et 40.99 ± 19.14 ans chez les femmes). Les renseignements cliniques les plus fréquemment reportés était le bilan rénal (33.20%) et le bilan infectieux (23.71%). Les indications moins fréquentes étaient l’infection pulmonaire et le choc septique. En fonction de la sévérité de l’infection mesurée par le taux de PCT, les résultats étaient les suivants: absence d’infection bactérienne (≤0,25 ng/ml) dans 33.99% des cas; infection bactérienne localisée (0.25 - 0.5 ng/ml) dans 5.53% des cas; infection bactérienne systémique (0.5 - 2 ng/ml) dans 14.23% des cas; sepsis sévère (2 - 10 ng/ml) dans 18.97% des cas et choc septique (>10 ng/ml) dans 27.27% des cas. Conclusion. Le dosage de la PCT a été prescrit essentiellement dans le cadre d’un bilan rénal et souvent aussi pour évaluer un état fébrile. Les valeurs de PCT étaient en règle prédictives de la présence d’une infection et permettaient de différencier entre infection localisée et affections systémiques.


Procalcitonin, prescription, infectious diseases, Bamako

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Boubacar Sidiki Ibrahim, D. ., Djibril Mamadou, C. ., Aboubacar, N. ., Yaya, G. ., Sow Djeneba , S., Adama, K. ., Kletigui Casimir, D. ., Aminata, M. ., Drissa, K. ., Oumar Agali, D. ., Daouda Kassoum, M. . ., & Bakary M, C. . (2022). Blood Procalcitonin Dosage in the Diagnosis of Infectious and Inflammatory Diseases in Bamako. HEALTH SCIENCES AND DISEASE, 23(3). Retrieved from


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